Genetics of Gestational Diabetes Mellitus and Type 2 Diabetes
نویسندگان
چکیده
منابع مشابه
Genetics of gestational diabetes mellitus and type 2 diabetes.
The successful application of positional cloning, the process of disease susceptibility gene identification using gene mapping techniques, to identify the gene underlying cystic fibrosis (1) opened the era of gene hunting. The subsequent identification of susceptibility genes underlying numerous monogenic disorders led to the possibility that susceptibility genes for complex diseases could also...
متن کاملGestational diabetes mellitus
Introduction: Gestational diabetes mellitus (GDM) is defined as any degree of glucose intolerance with onset or first recognition during pregnancy. The prevalence range from 1 to 14% of all pregnancies, depending on the population studied and the diagnostic tests employed. Risk assessment for GDM should be undertaken at the prenatal visit. Women with clinical characteristics of GDM should und...
متن کاملGestational Diabetes Mellitus: A Positive Predictor of Type 2 Diabetes?
The aim of this paper is to consider the relative benefits of screening for type two diabetes mellitus in women with a previous pregnancy complicated by gestational diabetes mellitus. Recent studies suggest that women who experience GDM are at a greater risk of developing type 2 diabetes within 10-20 years of their index pregnancy. If considered as a stand-alone indicator of the risk of develop...
متن کاملGenetics of type 2 diabetes mellitus.
The clinical picture of type 2 diabetes mellitus (T2DM) is formed by impairment in insulin secretion and resistance to insulin action. As a result of intensive efforts of the scientists around the world mutations and polymorphisms in a number of genes were linked with monogenic and polygenic forms of T2DM. Two major strategies were used in this research: genome scanning and the candidate gene a...
متن کاملGenetics of Type 2 Diabetes- A Review Article
Objective: Type 2 diabetes (T2D) as a complex disease is the result of genetically heterogeneous factors and environmental issues interaction. Linkage and small-scale candidate gene studies were successful in identification of genetic susceptibilities of monogenic form of diseases. However, they were largely unsuccessful while applying to the more common forms of disease. By designing Genome Wi...
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ژورنال
عنوان ژورنال: Diabetes Care
سال: 2007
ISSN: 0149-5992,1935-5548
DOI: 10.2337/dc07-s205